Master Class: Advances in Epidemiologic Analysis, Certificate

  • Application Deadline
  • 4 days
  • Tuition
    Tuition (Module)
    Tuition (Module)
  • English (take IELTS)
University rank #72 ,
In this Master Class course timely topics in study design of epidemiologic and clinical studies will be addressed. Four renowned faculty members will address advanced study design issues in a seminar format.


In former times, epidemiologists customarily published their data in a way that showed the distributions of key variables and their associations. Those days are mostly gone. From earlier papers, readers could see enough detail in the data to conduct their own analyses. This approach kept everyone informed and careful. Nowadays, it is usual for epidemiologists to present only derived results, typically from regression models, that cannot be checked from the published data. This gulf between epidemiologists and their data is conducive to publishing mistakes and obscures important information that readers should have.

The case-crossover study is designed to answer the question “Was event X triggered by something unusual that happened just before?” The key feature of the design is that each case serves as its own control. The method is analogous to a crossover experiment viewed retrospectively, except that the investigator does not control when a patient starts being exposed to a potential trigger.

The case-crossover study can also be compared with a traditional matched-pair case-control study. In both types of studies, each case has a matched control. In a traditional matched-pair case-control study, the control is a different individual at a similar time. In the matched-pair case-crossover design, the control is the same person at a different time. Decades of applied research have shown that the study design applies best when the exposure is intermittent, the effect of risk is immediate and transient, and the outcome is abrupt. Using the case-crossover design, investigators have been able to assess the extent to which episodes of physical exertion, anger, sexual activity, cocaine use, and alcohol consumption are triggers of myocardial infarctions. Others have applied the method to study triggers of other acute events including car crashes, injury, and adverse drug reactions. A placental abruption, for the most part, is an abrupt event that typically occurs in mid-to-late pregnancy; and is amenable for study using the case-crossover design.

Detailed Programme Facts

  • Languages
    • English
  • Delivery mode
    On Campus

Programme Structure

Admission is free, without registration:
  • Participants ESP 2013
  • Students NIHES programmes
  • Employees Erasmus MC
  • Public at large
  • Course code: ESP64
  • Date: August 12 15, 2015
  • Time: 16:30 18:00
  • Course days: Monday to Thursday
  • Location: To be announced
  • No course material


Albert Hofman

English Language Requirements

This programme requires students to demonstrate proficiency in English.

Take IELTS test

Academic Requirements

  • None

Tuition Fee Per Module

  • EUR 240 International
  • EUR 240 EU/EEA

Admission is free, without registrationm for: Participants ESP 2013, Students NIHES programmes, Employees Erasmus MC, Public at large


  • Each year, the Erasmus Summer Programme provides international students and professionals with an invaluable opportunity to spend three weeks in Holland, bringing themselves right up to date in the health sciences.
  • In just three weeks, the Erasmus Summer Programme provides 30 courses on state-of-the-art biomedical topics. Each course is designed to fully satisfy the needs of international students with a specific interest such as clinical medicine, general practice, public health, epidemiology, genetics or biostatistics.
  • A key part in the Erasmus Summer Programme is played by the Fellowships: three suites of courses that provide top-level instruction in clinical research training, public health research, and genetic epidemiology. Each Fellowship is a stimulating challenge for talented young scientists who seek leading careers in scientific research.
  • Between them, the Erasmus Summer Programme and the Fellowships make a vital contribution to life-long learning and the professional development of students and teachers. By attracting ever greater interest each year, they reveal the enormous international demand for a springboard to an MSc or PhD in quantitative medicine or public health research.

StudyPortals Tip: Students can search online for independent or external scholarships that can help fund their studies. Check the scholarships to see whether you are eligible to apply. Many scholarships are either merit-based or needs-based.