In the last decade, GWAS have yielded spectacular successes in the discovery of genes involved in complex traits and disorders (e.g. body height, BMI, cardiovascular disease, cancer and neurological disorders).
This was made possible by the advent of high-throughput genotyping technology and the knowledge on genome structure and organization derived from the HapMap and 1000 Genomes Projects. Applying the GWAS approach has facilitated researchers to incorporate these analyses into large genetic, clinical and epidemiological studies.
This Genome-wide association studies course from Erasmus University Rotterdam aims to introduce epidemiologists, molecular biologists and clinicians into the basic principles of GWAS, addressing aspects of study design, data collection and analysis, extending to the interpretation and follow-up of results.
The course consists of lectures providing a conceptual framework on crucial aspects of quality control, imputation of missing genotypes, statistical tools, methods to detect and correct for stratification, meta-analysis and genomic annotation of GWAS signals; accompanied by instructive hands-on computer exercises on the principles of analysis of quantitative traits and disease outcomes using software packages that are available in the public domain.
You can apply until:
Always verify the dates on the programme website.
This programme may require students to demonstrate proficiency in English.
Basic understanding of genetic epidemiology (as covered by ESP43), the principles of linkage disequilibrium and the HapMap & 1000 Genomes project (as covered by ESP57) is advised.
The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.
Studyportals Tip: Students can search online for independent or external scholarships that can help fund their studies. Check the scholarships to see whether you are eligible to apply. Many scholarships are either merit-based or needs-based.
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