Overview
In Spring 2011, thousands of people in Germany were hospitalized with a deadly disease that started as food poisoning with bloody diarrhea and often led to kidney failure. It was the beginning of the deadliest outbreak in recent history, caused by a mysterious bacterial strain that we will refer to as E. coli X. Soon, German officials linked the outbreak to a restaurant in Lübeck, where nearly 20% of the patrons had developed bloody diarrhea in a single week.
At this point, biologists knew that they were facing a previously unknown pathogen and that traditional methods would not suffice – computational biologists would be needed to assemble and analyze the genome of the newly emerged pathogen.
To investigate the evolutionary origin and pathogenic potential of the outbreak strain, researchers started a crowdsourced research program. They released bacterial DNA sequencing data from one of a patient, which elicited a burst of analyses carried out by computational biologists on four continents.
The 2011 German outbreak represented an early example of epidemiologists collaborating with computational biologists to stop an outbreak. In this Genome Assembly Programming Challenge , you will follow in the footsteps of the bioinformaticians investigating the outbreak by developing a program to assemble the genome of the E. coli X from millions of overlapping substrings of the E.coli X genome.
Skills You Will Gain after the Genome Assembly Programming Challenge course offered by Coursera in partnership with UC San Diego
- Data Structure
- Algorithms
- Algorithm Design
- String (Computer Science)
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Visit programme websiteProgramme Structure
Courses included:
- The 2011 European E. coli Outbreak
- Assembling Genomes Using de Bruijn Graphs
- Genome Assembly Faces Real Sequencing Data
Check out the full curriculum
Visit programme websiteKey information
Duration
- Part-time
- 1 days
Start dates & application deadlines
Language
Delivered
Disciplines
Computer Sciences Human Computer Interaction Web Technologies & Cloud Computing View 746 other Short Courses in Computer Sciences in United StatesExplore more key information
Visit programme websiteAcademic requirements
We are not aware of any specific GRE, GMAT or GPA grading score requirements for this programme.
English requirements
We are not aware of any English requirements for this programme.
Other requirements
General requirements
- Advanced level
- Designed for those already in the industry
Make sure you meet all requirements
Visit programme websiteTuition Fee
-
International
FreeTuition FeeBased on the tuition of 0 USD for the full programme during 1 days. -
National
FreeTuition FeeBased on the tuition of 0 USD for the full programme during 1 days.
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Funding
Coursera provides financial aid to learners who cannot afford the fee. Apply for it by clicking on the Financial Aid link beneath the "Enroll" button on the left. You'll be prompted to complete an application and will be notified if you are approved. You'll need to complete this step for each course in the Specialization, including the Capstone Project.