1 days
Duration
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About

This Comparing Genes, Proteins, and Genomes (Bioinformatics III) offered by Coursera in partnership with UC San Diego is part of the Bioinformatics Specialization.

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Overview

Once we have sequenced genomes in the previous course, we would like to compare them to determine how species have evolved and what makes them different.

In the first half of the Comparing Genes, Proteins, and Genomes (Bioinformatics III) offered by Coursera in partnership with UC San Diego, we will compare two short biological sequences, such as genes (i.e., short sequences of DNA) or proteins.  We will encounter a powerful algorithmic tool called dynamic programming that will help us determine the number of mutations that have separated the two genes/proteins.

In the second half of the course, we will "zoom out" to compare entire genomes, where we see large scale mutations called genome rearrangements, seismic events that have heaved around large blocks of DNA over millions of years of evolution.  

Looking at the human and mouse genomes, we will ask ourselves: just as earthquakes are much more likely to occur along fault lines, are there locations in our genome that are "fragile" and more susceptible to be broken as part of genome rearrangements?  We will see how combinatorial algorithms will help us answer this question.

Skills You Will Gain

  • Bioinformatics
  • Graph Theory
  • Bioinformatics Algorithms
  • Python Programming

Programme Structure

Courses include:

  • Sequence Alignment
  • From Finding a Longest Path to Aligning DNA Strings
  • Advanced Topics in Sequence Alignment
  • Genome Rearrangements and Fragility
  • Applying Genome Rearrangement Analysis to Find Genome Fragility
  • Bioinformatics Application Challenge

Key information

Duration

  • Part-time
    • 1 days

Start dates & application deadlines

You can apply for and start this programme anytime.

Language

English

Delivered

Online

What students do after studying

Academic requirements

We are not aware of any specific GRE, GMAT or GPA grading score requirements for this programme.

English requirements

We are not aware of any English requirements for this programme.

Other requirements

General requirements

  • Intermediate level
  • Some related experience required

Tuition Fee

To always see correct tuition fees
  • International

    Free
    Tuition Fee
    Based on the tuition of 0 USD for the full programme during 1 days.
  • National

    Free
    Tuition Fee
    Based on the tuition of 0 USD for the full programme during 1 days.

You can choose from hundreds of free courses, or get a degree or certificate at a breakthrough price. You can now select Coursera Plus, an annual subscription that provides unlimited access.

Funding

Coursera provides financial aid to learners who cannot afford the fee. Apply for it by clicking on the Financial Aid link beneath the "Enroll" button on the left. You'll be prompted to complete an application and will be notified if you are approved. You'll need to complete this step for each course in the Specialization, including the Capstone Project. 

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