Overview
Once we have sequenced genomes in the previous course, we would like to compare them to determine how species have evolved and what makes them different.
In the first half of the Comparing Genes, Proteins, and Genomes (Bioinformatics III) offered by Coursera in partnership with UC San Diego, we will compare two short biological sequences, such as genes (i.e., short sequences of DNA) or proteins. We will encounter a powerful algorithmic tool called dynamic programming that will help us determine the number of mutations that have separated the two genes/proteins.
In the second half of the course, we will "zoom out" to compare entire genomes, where we see large scale mutations called genome rearrangements, seismic events that have heaved around large blocks of DNA over millions of years of evolution.
Looking at the human and mouse genomes, we will ask ourselves: just as earthquakes are much more likely to occur along fault lines, are there locations in our genome that are "fragile" and more susceptible to be broken as part of genome rearrangements? We will see how combinatorial algorithms will help us answer this question.
Skills You Will Gain
- Bioinformatics
- Graph Theory
- Bioinformatics Algorithms
- Python Programming
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Visit programme websiteProgramme Structure
Courses include:
- Sequence Alignment
- From Finding a Longest Path to Aligning DNA Strings
- Advanced Topics in Sequence Alignment
- Genome Rearrangements and Fragility
- Applying Genome Rearrangement Analysis to Find Genome Fragility
- Bioinformatics Application Challenge
Check out the full curriculum
Visit programme websiteKey information
Duration
- Part-time
- 1 days
Start dates & application deadlines
Language
Delivered
Disciplines
Biology Information Technology (IT) Bioinformatics & Biostatistics View 378 other Short Courses in Information Technology (IT) in United StatesExplore more key information
Visit programme websiteWhat students do after studying
Academic requirements
We are not aware of any specific GRE, GMAT or GPA grading score requirements for this programme.
English requirements
We are not aware of any English requirements for this programme.
Other requirements
General requirements
- Intermediate level
- Some related experience required
Make sure you meet all requirements
Visit programme websiteTuition Fee
-
International
FreeTuition FeeBased on the tuition of 0 USD for the full programme during 1 days. -
National
FreeTuition FeeBased on the tuition of 0 USD for the full programme during 1 days.
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Funding
Coursera provides financial aid to learners who cannot afford the fee. Apply for it by clicking on the Financial Aid link beneath the "Enroll" button on the left. You'll be prompted to complete an application and will be notified if you are approved. You'll need to complete this step for each course in the Specialization, including the Capstone Project.