Overview
About the course
A comprehensive understanding of the principles of pharmacokinetics, pharmacokinetic/pharmacodynamic (PK/PD) relationships, and how to apply these principles to the design and evaluation of first-in-human single- and multiple dose studies is an essential component of the drug development process.
This includes assessment of the pharmacokinetics of new molecular entities, with consideration of demographic factors, drug-disease interactions and drug-drug interactions. Examples of these interactions will be communicated during the course with modelling of PK/PD of specific drugs based on data provided. The Theoretical and Practical Pharmacokinetics course is offered at King's College London.
Programme Structure
By the end of this module participants will be able to:- Design studies to assess absolute and relative bioavailability and be able to calculate whether formulations are bioequivalent.
- Interpret PK data obtained from a single dose escalation including dose proportionality, linearity and non-linearity.
- Understand how single dose data can be used to model the PK of repeated dosing, the importance of accumulation and fluctuation at steady state and the effects of changes in clearance and dose.
- Appraise the differences between the PK of small molecules and biologics.
- Appreciate the importance of robust handling of samples for assay and the bioanalytical techniques in common use.
- Understand how PK data in animals can be used to predict likely findings in humans.
- Understand the mechanisms involved in drug-drug interactions including effects on transporters and be able to use PK data to design such studies.
Key information
Duration
- Full-time
- 5 days
Start dates & application deadlines
- Available course dates: to be confirmed
Language
Delivered
Disciplines
Pharmacy Health Sciences Pharmacology View 587 other Short Courses in Health Sciences in United KingdomAcademic requirements
English requirements
We are not aware of any English requirements for this programme.
Student insurance
Make sure to cover your health, travel, and stay while studying abroad. Even global coverages can miss important items, so make sure your student insurance ticks all the following:
- Additional medical costs (i.e. dental)
- Repatriation, if something happens to you or your family
- Liability
- Home contents and baggage
- Accidents
- Legal aid
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Other requirements
General requirements
- Minimum entry requirements are either a medical degree (such as an MBBS) or a 2:1 first degree in pharmacy, pharmacology, biology, biochemistry, chemistry or related subject.
Tuition Fee
-
International
2590 GBP/fullTuition FeeBased on the tuition of 2590 GBP for the full programme during 5 days. -
National
1670 GBP/fullTuition FeeBased on the tuition of 1670 GBP for the full programme during 5 days.
Living costs for London
The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.