Overview
What you will study
An important task for bioengineers is to design and execute efficient and sustainable downstream processes to achieve a pure bioproduct. The desired purity and the biophysical characteristics of the product will have large effects on the design of the process. The Downstream processing of biological products course offered by KTH Royal Institute of Technology aims to give an understanding of the fundamentals of recovery/purification operations for biopharmaceutical production and how these operations are developed for use at production scale.
Examples of methods that will be discussed are:
- filtration, sedimentation, precipitation, centrifugation, extraction, crystallization and chromatography.
Intended learning outcomes:
- Describe, compare and understand a set of general methods used for downstream processing in large scale processing.
- Describe and explain the tasks a given unit operation can solve in a downstream process.
- Describe and motivate a set of general analytical tools used to track the downstream process.
Programme Structure
The program focuses on:
- different means for characterization of biological mixtures
- methods used for separation of solid and soluble phases
- technologies used to separate dissolved molecules from each other as well as methods utilized to concentrate the product
- how the biophysical properties of the target molecule as well as the contaminating molecules can be exploited in the design of an effective DSP will be presented
- the theoretical backgrounds of the methods as well as their practical use, advantages and drawbacks
- how demands on purity and yield of bio-products affect the design of the (DSP)
- the different possible choices of unit operations for downstream purification methods and how the used upstream methods will affect those
Key information
Duration
- Full-time
- 2 months
Start dates & application deadlines
- StartingApplication deadline not specified.
Language
Credits
Delivered
Disciplines
Biotechnology View 8 other Short Courses in Biotechnology in SwedenWhat students do after studying
Academic requirements
We are not aware of any specific GRE, GMAT or GPA grading score requirements for this programme.
English requirements
Student insurance
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- Additional medical costs (i.e. dental)
- Repatriation, if something happens to you or your family
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- Home contents and baggage
- Accidents
- Legal aid
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Other requirements
General requirements
- Bachelor's degree in technology or natural sciences containing 20 credits courses in biotechnology, 10 credits courses in mathematics, and 20 credits courses in chemistry.
- English B/6.
Tuition Fee
Living costs for Stockholm
The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.