
Overview
About the project
Cell adhesion occurs through spatio-temporally regulated interactions that are mediated by multiple intra- and inter-cellular components. Physiologically, shear forces on flowing cells orchestrate these interactions. The conventional assay used to study the effect of shear flow on cell adhesion is the parallel plate flow chamber (PPFC) assay, which records videos of cells rolling in flow and adhering to adhesion molecules on cells (eg. endothelial) or immobilized to a surface. However, due to the limited spatial resolution and sensitivity of these assays, nanoscopic molecular level mechanisms of selectin-selectin ligand interactions and their role in leukocyte (neutrophils, HSCs, T-cells) migration can’t be assessed.
Recent developments in super resolution and single-molecule fluorescence imaging techniques allow for the visualization of individual molecules with nanometer spatial resolution and millisecond temporal resolution. Furthermore, advanced super-resolution microscopy provides unique opportunities to obtain information about nanometer-scale conformational dynamics of protein complexes as well as nanoscale architectures of biological samples. In collaboration with S. Habuchi (BESE, KAUST)
The Capturing Adhesion Molecules in Action Through Imaging (Internship) project is offered at King Abdullah University Of Science and Technology (KAUST).
Get more details
Visit programme websiteProgramme Structure
- overall goal is to develop a platform for imaging cells in flow over tissue samples expressing selectins
- growth and maintenance of cell lines and primary cells
- prepare and stain tissue sections for selectins (E-/P-/L-selectin)
- prepare and stain cells lines for selectin ligands
- run flow assays and use super resolution imaging under the supervision of an experienced PhD student
Check out the full curriculum
Visit programme websiteKey information
Duration
- Part-time
- 3 months
Start dates & application deadlines
Students can choose their own start and end dates as the program runs across the year
Language
Delivered
Disciplines
Biomedical Science BiologyExplore more key information
Visit programme websiteWhat students do after studying
Academic requirements
English requirements
Other requirements
General requirements
- Official Transcript(s) in English from current and previous institutions
- Letter of Recommendation from faculty member in field of study
- Valid Passport(with six months validity)
- CV - Summary of your career, qualifications and education.
- Statement of Purpose-Explain your motivation to become a VSRP intern
Student insurance
Make sure to cover your health, travel, and stay while studying abroad. Even global coverages can miss important items, so make sure your student insurance ticks all the following:
- Additional medical costs (i.e. dental)
- Repatriation, if something happens to you or your family
- Liability
- Home contents and baggage
- Accidents
- Legal aid
We partnered with Aon to provide you with the best affordable student insurance, for a carefree experience away from home.
Get your student insurance nowStarting from €0.53/day, free cancellation any time.
Remember, countries and universities may have specific insurance requirements. To learn more about how student insurance work at King Abdullah University of Science and Technology (KAUST) and/or in Saudi Arabia, please visit Student Insurance Portal.
Make sure you meet all requirements
Visit programme websiteTuition Fee
-
International
FreeTuition FeeBased on the tuition of 0 SAR per year during 3 months. -
National
FreeTuition FeeBased on the tuition of 0 SAR per year during 3 months.
This is a fully-funded internship; it includes tuition, airfare, housing, medical insurance, visa reimbursement and a monthly stipend of $1,000.
Living costs for Thuwal
The living costs include the total expenses per month, covering accommodation, public transportation, utilities (electricity, internet), books and groceries.
Funding
The KAUST Fellowship includes:
- Full coverage of tuition and bench fees (worth USD $35,000 per year)
- A monthly stipend (worth USD $20,000 per year for PG Diploma and M.S. students, and USD $25,000 to $30,000 for Ph.D. students depending on qualifications and academic progress)
- On-campus housing (worth USD $7,000 per year and covering utilities such as electricity and wifi)
- Health insurance (worth USD $1,450 per year)
- Relocation support (visa, relocation and travel costs)